Бидридистроген ксебопарвовек

Rec. INN (наименование, зарегистрированное ВОЗ)

2365142-14-7

recombinant self-complementary (dimeric) non-replicating adeno-associated virus (AAV) serotype rh.74 vector encoding codon-optimized human beta-sarcoglycan (hSGCB) under control of a hybrid promoter (MHCK7) consisting of enhancer/promoter regions of murine muscle creatine kinase (CK) and alpha-myosin heavychain genes, followed by a chimeric intron, composed of the 5' donor site from the human beta-globin gene and the branchpoint and 3' splice acceptor site from IgG heavy chain variable region, and terminated by a small synthetic polyadenylation (polyA) signal sequence, flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats (ITRs).

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