Эбронуцимаб
EbronucimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Химическое название
immunoglobulin G1-lambda2, anti-[Homo sapiens PCSK9 (proprotein convertase subtilisin/kexin type 9, neural apoptosis-regulated convertase 1, NARC1, NARC-1, proprotein convertase 9, PC9)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-453) [VH (Homo sapiens IGHV3-21*01 (91.8%) -(IGHD) -IGHJ3*01 (100%)) CDR-IMGT [8.8.16] (26-33.51-58.97-112) (1-123) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (220) (124-221), hinge 1-15 (222-236), CH2 (237-346), CH3 D12 (362), L14 (364) (347-451), CHS (452-453)) (124-453)], (226-216')-disulfide with lambda2 light chain Homo sapiens (1'-217') [V-LAMBDA (Homo sapiens IGLV2-11*01 (81.6%) -IGLJ1*01 (90.9%)) CDR-IMGT [9.3.11] (26-34.52-54.91-101) (1'-111') -Homo sapiens IGLC2*01 (100%) (112’-217’)];
dimer (232-232":235-235")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain Homo sapiens (1-453) [VH (Homo sapiens IGHV3-21*01 (91.8%) -(IGHD) -IGHJ3*01 (100%)) CDR-IMGT [8.8.16] (26-33.51-58.97-112) (1-123) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (220) (124-221), hinge 1-15 (222-236), CH2 (237-346), CH3 D12 (362), L14 (364) (347-451), CHS (452-453)) (124-453)], (226-216')-disulfide with lambda2 light chain Homo sapiens (1'-217') [V-LAMBDA (Homo sapiens IGLV2-11*01 (81.6%) -IGLJ1*01 (90.9%)) CDR-IMGT [9.3.11] (26-34.52-54.91-101) (1'-111') -Homo sapiens IGLC2*01 (100%) (112’-217’)];
dimer (232-232":235-235")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Ebronucimabum (латинское)
- Ebronucimab (английское)
- Ebronucimab (немецкое)
- Ébronucimab (французское)
- Ebronucimab (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Эбронуцимаб: