Абдавомеран

Rec. INN (наименование, зарегистрированное ВОЗ)

2417899-75-1

messenger RNA (mRNA), 5'-capped, encoding the codon-optimised receptor binding domain (RBD) of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2, GenBank: MN908947.3) spike (S) glycoprotein, expressed as a fusion protein 5' with an extended S glycoprotein signal peptide and connected 3' by a glycine/serine (GS)-rich linker peptide with a T4 fibritin trimerization domain, flanked by 5' and 3' untranslated regions and a 3' poly(A) tail; contains N1-methylpseudouridine instead of uridine (all-U>m¹ Ψ).

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