Абипапоген суваплазмид

Prop. INN (наименование, предложенное ВОЗ)

2939766-18-2

DNA plasmid encoding a mutation-inactivated human papillomavirus type 16 E6 / E7 fusion protein linked to the human cytokine CCL3L1 (chemokine (C-C motif) ligand 3-like 1) via a dimerization module consisting of upper and lower hinge regions and constant heavy chain domain from human immunoglobulin G3 (IgG3). Expression of the transgene is under control of a cytomegalovirus (CMV) promoter/enhancer and terminated by a rabbit β-globin polyadenylation signal. The plasmid also contains a kanamycin resistance gene, an immunostimulatory (CpG-rich) sequence and a pUC origin of replication

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