Абирубарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2765071-95-0

immunoglobulin G4-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (115-212), hinge 1-12 S10>P (222) (213-224), CH2 L92 (303) (225-334), CH3 (335-439), CHS (440-441)) (115-441)], (128-213')-disulfide with kappa light chain humanized (1'-213') [V-KAPPA (Homo sapiens IGKV3-11*01 (82.1%) -IGKJ4*01 (91.7%), CDR-IMGT [5.3.9] (27'-31'.49'-51'.88'-96')) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152'), V101 (190') (107'-213')]; dimer (220-220'':223-223'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-DG44, glycoform alfa

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