Адинтревимаб
AdintrevimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Химическое название
immunoglobulin G1-lambda2, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV3-21*01 (88.8%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v24 CH3 L107, S114 (CH1 R120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 E12 (363), M14 (365), M107>L (435), N114>A (441) (348-452), CHS (453-454)) (125-453)], (227- 217')-disulfide with lambda2 light chain Homo sapiens (1'- 218') [V-LAMBDA (Homo sapiens IGLV1-40*01 (95.9%) - IGLJ1*01 (91.7%), CDR-IMGT [9.3.12] (26-34.52-54.91- 102)) (1'-112') -Homo sapiens IGLC2*01 (100%) (113'- 218')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV3-21*01 (88.8%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v24 CH3 L107, S114 (CH1 R120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 E12 (363), M14 (365), M107>L (435), N114>A (441) (348-452), CHS (453-454)) (125-453)], (227- 217')-disulfide with lambda2 light chain Homo sapiens (1'- 218') [V-LAMBDA (Homo sapiens IGLV1-40*01 (95.9%) - IGLJ1*01 (91.7%), CDR-IMGT [9.3.12] (26-34.52-54.91- 102)) (1'-112') -Homo sapiens IGLC2*01 (100%) (113'- 218')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Adintrevimabum (латинское)
- Adintrevimab (английское)
- Adintrevimab (немецкое)
- Adintrévimab (французское)
- Adintrevimab (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Адинтревимаб: