Алцестобарт

Prop. INN (наименование, предложенное ВОЗ)

2888563-73-1

immunoglobulin G4-kappa, anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223)], Homo sapiens monoclonal antibody;
H-gamma4 heavy chain Homo sapiens (1-439) [VH (Homo sapiens IGHV3-20*04 (91.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.5] (26-33.51-58.97-101)) (1-112) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (113-210), hinge 1-12 S10>P (220) (211-222), CH2 L92 (301) (223-332), CH3 (333-437), CHS (438-439)) (113-439)], (126-215')-disulfide with L-kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-39*01 (95.8%) -IGKJ2*01 (81.8%) EIK125-127>TVLG (105'-108'), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-108') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (154'), V101 (192')) (109'-215')]; dimer (218-218'':221-221'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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