Алдастотуг

Prop. INN (наименование, предложенное ВОЗ)

2865844-59-1

immunoglobulin G1-kappa, anti-[Homo sapiens SIGLEC15 (sialic acid-binding Ig-like lectin 15, CD33-like 3, CD33L3)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV5-10-1*01 (95.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222-215')-disulfide with L-kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (94.8%) -IGKJ1*01 (90.9%) I126>F (107'), CDR-IMGT [7.3.9] (27'-33'.51'-53'.90'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154'), V101 (192') (109'-215')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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