Алетекитуг

Prop. INN (наименование, предложенное ВОЗ)

2923284-67-5

immunoglobulin G1-kappa, anti-[Homo sapiens IL18 (interleukin 18, IL-18, interferon gamma-inducing factor, IGIF, interleukin-1 gamma, IL-1G, IL1F4)], humanized monoclonal antibody;
H-gamma1 heavy chain humanized (1-456) [VH (Homo sapiens IGHV1-24*01 (82.7%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.19] (26-33.51-58.97-115)) (1-126) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (223) (127-224), hinge 1-15 (225-239), CH2 (240-349), CH3 D12 (365), L14 (367) (350-454), CHS (455-456)) (127-456)], (229-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (83.2%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (235-235'':238-238'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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