Аломфилимаб
AlomfilimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Drugbank
DB16681
CAS
2378692-24-9
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens ICOS (inducible T-cell costimulatory, activation-inducible lymphocyte immunomediatory molecule, AILIM, CD278)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV3-20*04 (94.9%) -(IGHD) -IGHJ4*01 (92.9%) T122>I (118)) CDR-IMGT [8.8.17] (26-33.51-58.97-113) (1-124) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 D12 (363), L14 (365) (348-452), CHS (453-454)) (125-454)], (227-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (92.7%) -IGKJ3*01 (100%)) CDR-IMGT [7.3.9] (27-33.51-53.90-98) (1'-108') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (154), V101 (192) (109'-215')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV3-20*04 (94.9%) -(IGHD) -IGHJ4*01 (92.9%) T122>I (118)) CDR-IMGT [8.8.17] (26-33.51-58.97-113) (1-124) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 D12 (363), L14 (365) (348-452), CHS (453-454)) (125-454)], (227-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (92.7%) -IGKJ3*01 (100%)) CDR-IMGT [7.3.9] (27-33.51-53.90-98) (1'-108') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (154), V101 (192) (109'-215')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Alomfilimabum (латинское)
- Alomfilimab (английское)
- Alomfilimab (немецкое)
- Alomfilimab (французское)
- Alomfilimab (испанское)
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