Амдокитуг

Prop. INN (наименование, предложенное ВОЗ)

3012586-05-6

immunoglobulin G1-kappa, anti-[Homo sapiens IL17A (Interleukin 17A, IL-17)], monoclonal antibody;
H-gamma1 heavy chain (1-445) [VH (Homo sapiens IGHV3-23*04 (89.8%) -(IGHD) -IGHJ5*01 (100%), CDR-IMGT [8.7.9] (26-33.51-57.96-104)) (1-115) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (212) (116-213), hinge 1-15 (214-228), CH2 (229-338), CH3 E12 (354), M14 (356) (339-443), CHS (444-445)) (116-445)], (218-214')-disulfide with L-kappa light chain (1'-214') [V-KAPPA Musmus/Homsap (Mus musculus IGKV13-85*01 (87.4%) -IGKJ4*01 (100%)/Homo sapiens IGKV1-NL1*01 (87.4%) -IGKJ2*02 (90.9%) Q120>S (100'), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (224-224'': 227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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