Амленетуг

Prop. INN (наименование, предложенное ВОЗ)

2850367-41-6

immunoglobulin G1-kappa, anti-[Homo sapiens SNCA (synuclein alpha, PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein alpha (non A4 component of amyloid precursor))], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-23*01 (90.8%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 E12 (355), M14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-215')-disulfide with L-kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (100%) -IGKJ1*01 (100%), CDR-IMGT [7.3.9] (27'-33'.51'-53'.90'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154'), V101 (192') (109'-215')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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