Амлителимаб
AmlitelimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2378692-15-8
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens TNFSF4 (tumor necrosis factor (TNF) superfamily member 4, OX40 ligand, OX-40L, TAX transcriptionally-activated glycoprotein 1, TXGP1, CD252)], monoclonal antibody;
gamma4 heavy chain (1-454) [VH (Homo sapiens IGHV3-23*04 (89.8%) -(IGHD) -IGHJ6*01 (100%)) CDR-IMGT [8.8.20] (26-33.51-58.97-116) (1-127) -Homo sapiens IGHG4*01, G4v5 h P10, G4v3 E1.2 (CH1 (128-225), hinge 1-12 S10>P (235) (226-237), CH2 L1.2>E (242) (238-347), CH3 (348-452), CHS (453-454)) (128-454)], (210-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (96.8%) -IGKJ3*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma4 heavy chain (1-454) [VH (Homo sapiens IGHV3-23*04 (89.8%) -(IGHD) -IGHJ6*01 (100%)) CDR-IMGT [8.8.20] (26-33.51-58.97-116) (1-127) -Homo sapiens IGHG4*01, G4v5 h P10, G4v3 E1.2 (CH1 (128-225), hinge 1-12 S10>P (235) (226-237), CH2 L1.2>E (242) (238-347), CH3 (348-452), CHS (453-454)) (128-454)], (210-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (96.8%) -IGKJ3*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Amlitelimabum (латинское)
- Amlitelimab (английское)
- Amlitelimab (немецкое)
- Amlitélimab (французское)
- Amlitelimab (испанское)
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