Анетумаб кориксетан
Anetumab corixetanМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2222980-98-3
Химическое название
immunoglobulin G1-lambda2, anti-[Homo sapiens MSLN (mesothelin, pre-pro-megakaryocyte-potentiating factor, megakaryocyte-potentiating factor, MPF, CAK1)], Homo sapiens monoclonal antibody, conjugated to chelator corixetan;
gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV5-51*01 (94.9%) -(IGHD) -IGHJ4*01 (86.7%)) [8.8.13] (1-120) -Homo sapiens IGHG1*01 (100%) G1m17,1 (CH1 K120 (217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359) L14 (361) (344-448), CHS (449-450)) (121-450)], (223-216')-disulfide with lambda light chain Homo sapiens (1'-217') [V-LAMBDA (Homo sapiens IGLV2-14*01 (95.6%) -IGKJ2*01 (100%)) [9.3.11] (1'-111') -Homo sapiens IGLC2*01 (99.1%) A43>G (155) (112'-217')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese Hamster Ovary (CHO)-S cell line, glycoform alfa; conjugated to chelator corixetan, with an average of 0.5 chelator per antibody
gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV5-51*01 (94.9%) -(IGHD) -IGHJ4*01 (86.7%)) [8.8.13] (1-120) -Homo sapiens IGHG1*01 (100%) G1m17,1 (CH1 K120 (217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359) L14 (361) (344-448), CHS (449-450)) (121-450)], (223-216')-disulfide with lambda light chain Homo sapiens (1'-217') [V-LAMBDA (Homo sapiens IGLV2-14*01 (95.6%) -IGKJ2*01 (100%)) [9.3.11] (1'-111') -Homo sapiens IGLC2*01 (99.1%) A43>G (155) (112'-217')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese Hamster Ovary (CHO)-S cell line, glycoform alfa; conjugated to chelator corixetan, with an average of 0.5 chelator per antibody
Структура
Иностранные названия
- Anetumabum corixetanum (латинское)
- Anetumab corixetan (английское)
- Anetumab corixetan (немецкое)
- Anétumab corixétan (французское)
- Anetumab corixetán (испанское)
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