Анивоветмаб

Rec. INN (наименование, зарегистрированное ВОЗ)

2370896-63-0

immunoglobulin G2-kappa, anti-[canine (Canis lupus familiaris) parvovirus major capsid protein VP2)], chimeric monoclonal antibody;
gamma2 heavy chain chimeric (1-457) [VH Ratnor/Canlupfam (Rattus norvegicus IGHV2-32*01 (92.8%) -(IGHD) -IGHJ3*01 (92.9%)/Canis lupus familiaris IGHV4- 1*01 (60.2%) -(IGHD) -IGHJ5*01 (92.9%), CDR-IMGT [8.7.16] (26-33.51-57.96-111)) (1-122) -Canis lupus familiaris IGHG2*02 (100%) (CH1 (123-219), hinge 1-19 (220-238), CH2 (239-348), CH3 (349-455), CHS (456-457)) (123-457)], (137-213')-disulfide with kappa light chain chimeric (1'-217') [V-KAPPA Ratnor/Canlupfam (Rattus norvegicus IGKV6S10*01 (95.8%) -IGKJ5*01 (100%)/Canis lupus familiaris IGKV3-18*01 (65.6%) -IGKJ3*01 (83.3%), CDR- IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Canis lupus familiaris IGKC*01 (100%) (108'-217')]; dimer (234-234'':237-237'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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