Ансувимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

DB16385

2375952-29-5

immunoglobulin G1-kappa, anti-[Zaire ebolavirus (Zaire Ebola virus (EBOV)) )) envelope glycoprotein subunit 1 (GP1) glycan cap domain], monoclonal antibody;
gamma1 heavy chain (1-449) [VH (Homo sapiens IGHV3-13*01 (78.4%) -(IGHD) -IGHJ5*01 (92.9%) T122>I (113)) CDR-IMGT [8.7.13] (26-33.51-57.96-108) (1-119) -Homo sapiens IGHG1*01 (100%) G1m17,1 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-27*01 (87.4%) -IGKJ4*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa

C₆₃₆₈H₉₉₂₄N₁₇₂₄O₁₉₉₄S₄₄

143 950 0,15 г/моль

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