Атенастобарт

Prop. INN (наименование, предложенное ВОЗ)

2817644-49-6

immunoglobulin G1-lambda2, anti-[Homo sapiens TNFRSF9 (TNF receptor superfamily member 9, 4-1BB, T cell antigen ILA, CD137)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-21*01 (90.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v85 CH2 W1.2, N1.1, D30, K115, G1v87 CH2 R94, CH3 R1.2 (CH1 R120 (219) (123-220), hinge 1-15 (221-235), CH2 L1.2>W (240), G1.1>N (241), H30>D (273), Q94>R (316), A115>K (335) (236-345), CH3 E12 (361), M14 (363), P1.2>R (348) (346-450), CHS G1>del, K2>del) (123-450)], (225-215')-disulfide with L-lambda2 light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV2-8*01 (93.5%) -IGLJ3*02 (100%), CDR-IMGT [9.3.10] (26'-34'.52'-54'.91'-100')) (1'-110') -Homo sapiens IGLC2*01 (100%) (C-LAMBDA2) (111'-216')]; dimer (231-231'':234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DXB11, glycoform alfa

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