Атибуклимаб
AtibuclimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Drugbank
DB06546
CAS
2417175-94-9
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens CD14, membrane (mCD14) and soluble (sCD14)], chimeric monoclonal antibody;
gamma4 heavy chain chimeric (1-442) [VH Mus musculus (Musmus IGHV3-2*02 (95.9%) -(IGHD) -Musmus IGHJ3*01 (92.9%) A128>S (115)) CDR-IMGT [9.7.8] (26-34.52-58.97-104) (1-115) -Homo sapiens IGHG4*01 (100%), CH1 (116-213), hinge 1-12 (214-225), CH2 (226-335), CH3 (336-440), CHS (441-442)) (116-442)], (129-218')-disulfide with kappa light chain chimeric (1’-218’) [V-KAPPA Mus musculus (Musmus IGKV3-5*01 (97.0%) -IGKJ2*01 (100%)) CDR-IMGT [10.3.9] (27-36.54-56.93-101) (1'-111') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (221-221":224-224")-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
gamma4 heavy chain chimeric (1-442) [VH Mus musculus (Musmus IGHV3-2*02 (95.9%) -(IGHD) -Musmus IGHJ3*01 (92.9%) A128>S (115)) CDR-IMGT [9.7.8] (26-34.52-58.97-104) (1-115) -Homo sapiens IGHG4*01 (100%), CH1 (116-213), hinge 1-12 (214-225), CH2 (226-335), CH3 (336-440), CHS (441-442)) (116-442)], (129-218')-disulfide with kappa light chain chimeric (1’-218’) [V-KAPPA Mus musculus (Musmus IGKV3-5*01 (97.0%) -IGKJ2*01 (100%)) CDR-IMGT [10.3.9] (27-36.54-56.93-101) (1'-111') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (221-221":224-224")-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
Структура
Иностранные названия
- Atibuclimabum (латинское)
- Atibuclimab (английское)
- Atibuclimab (немецкое)
- Atibuclimab (французское)
- Atibuclimab (испанское)
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