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Rec. INN (наименование, зарегистрированное ВОЗ)

2733581-82-1

immunoglobulin G1-kappa, anti-[Fucosyl-GM1 (fucosylated monosialoganglioside 1)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV3-48*02 (90.7%) -(IGHD) -IGHJ3*01 (92.3%) M123>T (117), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (219) (123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 E12 (361), M14 (363) (346-450), CHS (451-452)) (123-452)], (225-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1D-16*01 (100%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153'), V101 (191') (108'-214')]; dimer (231-231'':234-234'')-bisdisulfide, produced in a Chinese hamster ovary (CHO) cell line lacking the enzyme alpha-(1,6)-fucosyltransferase (FUT8), glycoform alfa

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