Ауденцел

Rec. INN (наименование, зарегистрированное ВОЗ)

autologous interleukin (IL)-12-secreting dendritic cells (DCs), loaded with autologous tumour lysate, comprising >70% of total immune cells. The cells are differentiated from autologous monocytes by culturing in the presence of interleukin (IL)-4 and GM-CSF (granulocyte-macrophage colony-stimulating factor), following which they are exposed to the patient's tumor protein/tumor-associated antigen (TAA), and subsequently to lipopolysaccharide (LPS) in the presence of interferon gamma (IFN-γ) to enable IL-12 secretion.

Поделиться этой страницей