Азинтуксизумаб

Rec. INN (наименование, зарегистрированное ВОЗ)

immunoglobulin G1-kappa, anti-[Homo sapiens SLAMF7 (SLAM family member 7, CD2 subset 1, CS1, CD2-like receptor-activating cytotoxic cells, CRACC, 19A24, CD319)], humanized and chimeric monoclonal antibody; gamma1 heavy chain (1-447) [humanized VH (Homo sapiens IGHV3-7*01 (91.80%) -(IGHD) -IGHJ4*01 L123>T (112) [8.8.10] (1-117) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (214) (118-215), hinge (216-230), CH2 (231-340), CH3 E12(366), M14 (368) (341-445), CHS (446-447) (118-447)], (220-220')- disulfide with kappa light chain chimeric (1'-220') [Mus musculus V-KAPPA (IGKV1-110*01 (93.00%) -IGKJ4*01) [11.3.10] (1'-113') -Homo sapiens IGKC*01, Km3 A45.1 (159), V101 (197) (114'-220')]; dimer (226-226'':229-229'')- bisdisulfide

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