Бапотулимаб
BapotulimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2359413-58-2
Химическое название
immunoglobulin G2-kappa, anti-[Homo sapiens ILDR2 (immunoglobulin like domain containing receptor 2, C1orf32)], Homo sapiens monoclonal antibody;
gamma2 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV1-69*10 (100%) -(IGHD) -IGHJ5*01 (81.2%)) CDR-IMGT [8.8.13] (26-33.51-58.97-109) (1-120) -Homo sapiens IGHG2*01, G2m.. CH2 V45.1 (CH1 (121-218), hinge 1-12 (219-230), CH2 V45.1 (281) (231-339), CH3 (340-444), CHS K>del (445)) (121-445)], (134-219’)-disulfide with kappa light chain Homo sapiens (1’-219’) [V-KAPPA (Homo sapiens IGKV2-28*01 (99%) -IGKJ4*01 (83.3%)) CDR-IMGT [11.3.9] (27-37.55-57.94-102) (1’-112’) -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113’-219’)]; dimer (222-222":223-223":226-226":229-229")-tetrakisdisulfide, produced in a Chinese Hamster Ovary (CHO)-derived cell line, glycoform alfa
gamma2 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV1-69*10 (100%) -(IGHD) -IGHJ5*01 (81.2%)) CDR-IMGT [8.8.13] (26-33.51-58.97-109) (1-120) -Homo sapiens IGHG2*01, G2m.. CH2 V45.1 (CH1 (121-218), hinge 1-12 (219-230), CH2 V45.1 (281) (231-339), CH3 (340-444), CHS K>del (445)) (121-445)], (134-219’)-disulfide with kappa light chain Homo sapiens (1’-219’) [V-KAPPA (Homo sapiens IGKV2-28*01 (99%) -IGKJ4*01 (83.3%)) CDR-IMGT [11.3.9] (27-37.55-57.94-102) (1’-112’) -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113’-219’)]; dimer (222-222":223-223":226-226":229-229")-tetrakisdisulfide, produced in a Chinese Hamster Ovary (CHO)-derived cell line, glycoform alfa
Структура
Иностранные названия
- Bapotulimabum (латинское)
- Bapotulimab (английское)
- Bapotulimab (немецкое)
- Bapotulimab (французское)
- Bapotulimab (испанское)
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