Барецетамаб
BarecetamabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Химическое название
immunoglobulin G1-lambda, anti-[Homo sapiens ERBB3 (receptor tyrosine-protein kinase erbB-3, HER3)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV3-23*01 (90.8%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.8.14] (26-33.51-58.97-110) (1-121) -Homo sapiens IGHG1*01, nG1m1, G1m17 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-215')-disulfide with lambda light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV1-47*02 (92.9%) -IGLJ2*01 (100%)) CDR-IMGT [8.3.11] (26-33.51-53.90-100) (1’-110’) -Homo sapiens IGLC3*03 (100%) (111'-216')];
dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese Hamster Ovary (CHO)-K1 cell line, glycoform alfa
gamma1 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV3-23*01 (90.8%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.8.14] (26-33.51-58.97-110) (1-121) -Homo sapiens IGHG1*01, nG1m1, G1m17 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-215')-disulfide with lambda light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV1-47*02 (92.9%) -IGLJ2*01 (100%)) CDR-IMGT [8.3.11] (26-33.51-53.90-100) (1’-110’) -Homo sapiens IGLC3*03 (100%) (111'-216')];
dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese Hamster Ovary (CHO)-K1 cell line, glycoform alfa
Структура
Иностранные названия
- Barecetamabum (латинское)
- Barecetamab (английское)
- Barecetamab (немецкое)
- Barécétamab (французское)
- Barecetamab (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Барецетамаб: