Базиликсимаб сароталокан

Rec. INN (наименование, зарегистрированное ВОЗ)

2417483-64-6

immunoglobulin G1-kappa, anti-[Homo sapiens IL2RA (interleukin 2 receptor subunit alpha; IL-2RA, TAC, p55, CD25)], chimeric monoclonal antibody conjugated to IRDye 700DX (IR700) near-infrared photosensitizing dye;
gamma1 heavy chain chimeric (1-447) [VH (Mus musculus IGHV1-5*01 (92.9%) -(IGHD) -IGHJ2*01 (93.3%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (214) (118-215), hinge 1-15 (216-230), CH2 (231-340), CH3 E12 (356), M14 (358) (341-445), CHS (446-447)) (118-447)], (220-211')-disulfide with kappa light chain chimeric (1'-211') [V-KAPPA (Mus musculus IGKV4-70*01 (98.9%) -IGKJ1*01 (100%), CDR-IMGT [11.3.10] (27-31.49-51.88-94)) (1'-104') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (150), V101 (188) (105'-211')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa; conjugated on an average of 2 or 3 lysyl to photosensitizing dye IRDye 700DX

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