Батираксцепт

Rec. INN (наименование, зарегистрированное ВОЗ)

human tyrosine-protein kinase receptor UFO (AXL oncogene) fragment (8-202, 1-195 in the current sequence), variant (G¹⁴>S⁷, A⁵⁴>V⁴⁷, D⁶⁹>G⁶², V⁷⁴>A⁶⁷, G¹⁰⁹>R¹⁰²), fused via peptidyl linker (¹⁹⁶GGGGS²⁰⁰) to a human immunoglobulin G1 Fc fragment (201-426, C-terminal Lys residue deleted), dimer, glycosylated, produced in Chinese hamster ovary (CHO) cells; [G¹⁴>S(7), A⁵⁴>V(47), D⁶⁹>G(62), V⁷⁴>A(67), G¹⁰⁹>R(102)] human AXL receptor tyrosine kinase (AXL oncogene, tyrosineprotein kinase receptor UFO) (8-202)-peptide (1-195), fused via a G4S linker (196-200) to a human immunoglobulin G1 Cterminal K>del Fc fragment (201-426), dimer (206-206':209-209')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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