Бемпикибарт
BempikibartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2622254-57-1
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens IL7R (interleukin 7 receptor, IL7RA, CD127)], Homo sapiens antibody;
gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-9*01 (96%) -(IGHD) -IGHJ1*01 (90.9%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v43 CH2 A1.3, E1.2, A1 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 L1.3>A (238), L1.2>E (239), G1>A (241) (235-344), CH3 E12 (360), M14 (362) (345-449), CHS K2>del (450)) (122-450)], (224-216')-disulfide with kappa light chain Homo sapiens (1'-216') [V-KAPPA (Homo sapiens IGKV1-13*02 (100%) -IGKJ5*01 (100%), CDR-IMGT [6.3.11] (27-32.50-52.89-99)) (1'-109') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (155), V101 (193) (110'-216')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derivative of the cell line CHO-K1, glycoform alfa
gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-9*01 (96%) -(IGHD) -IGHJ1*01 (90.9%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v43 CH2 A1.3, E1.2, A1 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 L1.3>A (238), L1.2>E (239), G1>A (241) (235-344), CH3 E12 (360), M14 (362) (345-449), CHS K2>del (450)) (122-450)], (224-216')-disulfide with kappa light chain Homo sapiens (1'-216') [V-KAPPA (Homo sapiens IGKV1-13*02 (100%) -IGKJ5*01 (100%), CDR-IMGT [6.3.11] (27-32.50-52.89-99)) (1'-109') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (155), V101 (193) (110'-216')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derivative of the cell line CHO-K1, glycoform alfa
Структура
Иностранные названия
- Bempikibartum (латинское)
- Bempikibart (английское)
- Bempikibart (немецкое)
- Bempikibart (французское)
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