Бетинукибарт

Prop. INN (наименование, предложенное ВОЗ)

2744274-11-9

immunoglobulin G1-kappa, anti-[Homo sapiens IL17A (interleukin 17A, IL-17A)];
H-gamma1 heavy chain (1-447) [VH (Homo sapiens IGHV7-4-1*02 (90.7%) -(IGHD) -IGHJ4*01 (93.3%) L123>T (112), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v14 CH2 A1.3, A1.2 (CH1 R120 (214) (118-215), hinge (216-230), CH2 L1.3>A (234), L1.2>A (235) (231-340), CH3 E12 (356), M14 (358) (341-445), CHS (446-447)) (118-447)], (220-219')-disulfide with L-kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-110*01 (89.0%) -IGKJ2*01 (100%)/Homo sapiens IGKV2-28*01 (82.0%) -IGKJ2*01 (91.7%) Q120>G (105'), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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