Бевуфеноген нофепарвовек
Bevufenogene nofeparvovecМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2374772-30-0
Химическое название
A non-replicating, recombinant adeno-associated virus expressing codon-optimised human phenylalanine hydroxylase (PAH).
A non-replicating, recombinant adeno-associated virus, hematopoietic stem cell serotype 15 (AAVHSC15) expressing codon-optimised human phenylalanine hydroxylase (PAH) under control of a liver-specific hybrid promoter [comprising human hepatic control region-1 (HCR-1) enhancer element, human alpha-1-antitrypsin (hAAT) promoter and the SV40 small t intron)] and an SV40 polyA signal sequence, flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats (ITRs).
A non-replicating, recombinant adeno-associated virus, hematopoietic stem cell serotype 15 (AAVHSC15) expressing codon-optimised human phenylalanine hydroxylase (PAH) under control of a liver-specific hybrid promoter [comprising human hepatic control region-1 (HCR-1) enhancer element, human alpha-1-antitrypsin (hAAT) promoter and the SV40 small t intron)] and an SV40 polyA signal sequence, flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats (ITRs).
Структура
Иностранные названия
- Bevufenogenum nofeparvovecum (латинское)
- Bevufenogene nofeparvovec (английское)
- Bevufenogen nofeparvovec (немецкое)
- Bévufénogène noféparvovec (французское)
- Bevufenogén nofeparvovec (испанское)
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