Биринкибарт

Prop. INN (наименование, предложенное ВОЗ)

2894136-82-2

immunoglobulin G4-kappa, anti-[Homo sapiens CSF2RB (colony stimulating factor 2 (CSF2) receptor subunit beta, granulocyte-macrophage colony stimulating factor (GM-CSF) receptor subunit beta, beta common cytokine receptor, IL3RB, IL5RB, CD131)], Homo sapiens monoclonal antibody;
H-gamma4 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV1-24*01 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (124-221), hinge 1-12 S10>P (231) (222-233), CH2 L92 (312) (234-343), CH3 (344-448), CHS (449-450)) (124-450)], (137-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (93.8%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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