Биртамимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

DB16414

1608108-91-3

immunoglobulin G1-kappa, anti-[Homo sapiens serum amyloid A (AA) and immunoglobulin amyloid light chain (AL)], monoclonal antibody;
gamma1 heavy chain (1-449) [VH (Mus musculus IGHV10-1*02 (89.8%)/Homo sapiens IGHV3-72*01 (84.0%) -(IGHD) -Homo sapiens IGHJ4*01 (92.9%)) [8.10.10] (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 (CH1 R120 (216) (120-217), hinge (218-232), CH2 (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448- 449)) (120-449)], (222-219')-disulfide with kappa light chain (1'-219') [V-KAPPA (Mus musculus IGKV1-110*01 (91.0%)/Homo sapiens IGKV2-30*02 (87.0%) -Homo sapiens IGKJ4*01 (91.7%)) [11.3.9] (1'-112') -Homo sapiens IGKC*01, Km3A45.1 (158), V101 (196)(113'-219')]; dimer (228-228'':231-231'')-bisdisulfide

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