Бривестобарт
BrivestobartМНН
Prop. INN (наименование, предложенное ВОЗ)
CAS
2786639-04-9
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223)], Homo sapiens monoclonal antibody;
H-gamma4 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV4-34*01 (91.8%) -(IGHD) -IGHJ5*01 (92.3%), CDR-IMGT [8.7.15] (26-33.51-57.96-110)) (1-121) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (122-219), hinge 1-12 S10>P (229) (220-231), CH2 L92 (310) (232-341), CH3 (342-446), CHS (447-448)) (122-448)], (135-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-11*01 (95.8%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
H-gamma4 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV4-34*01 (91.8%) -(IGHD) -IGHJ5*01 (92.3%), CDR-IMGT [8.7.15] (26-33.51-57.96-110)) (1-121) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (122-219), hinge 1-12 S10>P (229) (220-231), CH2 L92 (310) (232-341), CH3 (342-446), CHS (447-448)) (122-448)], (135-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-11*01 (95.8%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Структура
Иностранные названия
- Brivestobartum (латинское)
- Brivestobart (английское)
- Brivestobart (немецкое)
- Brivestobart (французское)
- Brivestobart (испанское)
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