Бронтиктузумаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB12737

1447814-75-6

immunoglobulin G2-lambda, anti-[Homo sapiens NOTCH1 (Notch 1, Translocation-associated notch-1, TAN1,TAN1)], humanized monoclonal antibody;
gamma2 heavy chain (1-447) [humanized VH (Homo sapiens IGHV1-24*01 (80.40%) -(IGHD)-IGHJ4*01 L123>T (116)) [8.8.14] (1-121) -Homo sapiens IGHG2*01 (CH1 (122-219), hinge (220-231), CH2 (232-340), CH3 (341- 445), CHS (446-447)) (122-447)],(135-214')-disulfide with lambda light chain (1'-215’) [humanized V-LAMBDA (Homo sapiens IGLV7-46*01 (83.20%) -IGLJ2*01) [9.3.9] (1'-109') -Homo sapiens IGLC7*01 (110'-215')]; dimer (223- 223'':224-224'':227-227'':230-230'')-tetrakisdisulfide

C₆₃₉₂H₉₈₆₂N₁₉₈₀O₁₇₁₀S₅₀

143410,36 г/моль

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