Бурфиралимаб
BurfiralimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2460809-80-5
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens VIM (vimentin)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-2*06 (86.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01 (100%) (CH1 (119-216), hinge 1-12 (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (85.3%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
gamma4 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-2*06 (86.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01 (100%) (CH1 (119-216), hinge 1-12 (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (85.3%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
Структура
Иностранные названия
- Burfiralimabum (латинское)
- Burfiralimab (английское)
- Burfiralimab (немецкое)
- Burfiralimab (французское)
- Burfiralimab (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Бурфиралимаб: