Кафелкибарт

Prop. INN (наименование, предложенное ВОЗ)

2851855-89-3

immunoglobulin G1-kappa, anti-[Homo sapiens CCR8 (C-C motif chemokine receptor 8, CKR-L1, CDw198)];
H-gamma1 heavy chain (1-453) [VH Musmus/Homsap (Mus musculus IGHV10-1*02 (92.9%) -(IGHD) -IGHJ4*01 (93.8%) S123>L (118)/Homo sapiens IGHV3-73*01 (88.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.10.14] (26-33.51-60.99-112)) (1-123) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v7 CH2 D3, E117 (CH1 K120 (220) (124-221), hinge 1-15 (222-236), CH2 S3>D (245), I117>E (338) (237-346), CH3 D12 (362), L14 (364) (347-451), CHS (452-453)) (124-453)], (226-219')-disulfide with L-kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV2-137*01 (91.0%) -IGKJ4*01 (91.7%) S120>Q (115')/Homo sapiens IGKV2-28*01 (87.0%) -IGKJ2*02 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158'), V101 (196') (113'-219')]; dimer (232-232'':235-235'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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