Камотескимаб
CamoteskimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2492472-82-7
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens IL18 (interleukin 18, IL-18, interferon gamma-inducing factor, IGIF, interleukin-1 gamma, IL-1γ, IL1F4)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV4-39*01 (91.9%) -(IGHD) -IGHJ2*01 (86.7%), CDR-IMGT [10.7.17] (26-35.53-59.98-114)) (1-125) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v39 CH2 F1.3, E1.2, S116 (CH1 A1.4>S (127), S1.3>T (128), T1.2>K (129), K1.1>C (130), G1>L (131), R120 (222) (126-223), hinge 1-15 (224-238), CH2 L1.3>F (242), L1.2>E (243), P116>S (339) (239-348), CH3 E12 (364), M14 (366) (349-453), CHS (454-455)) (126-455)], (228-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*03 (96.7%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (234-234'':237-237'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV4-39*01 (91.9%) -(IGHD) -IGHJ2*01 (86.7%), CDR-IMGT [10.7.17] (26-35.53-59.98-114)) (1-125) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v39 CH2 F1.3, E1.2, S116 (CH1 A1.4>S (127), S1.3>T (128), T1.2>K (129), K1.1>C (130), G1>L (131), R120 (222) (126-223), hinge 1-15 (224-238), CH2 L1.3>F (242), L1.2>E (243), P116>S (339) (239-348), CH3 E12 (364), M14 (366) (349-453), CHS (454-455)) (126-455)], (228-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*03 (96.7%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (234-234'':237-237'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
Структура
Иностранные названия
- Camoteskimabum (латинское)
- Camoteskimab (английское)
- Camoteskimab (немецкое)
- Camoteskimab (французское)
- Camoteskimab (испанское)
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