Канвирцепт

Rec. INN (наименование, зарегистрированное ВОЗ)

2833647-10-0

human angiotensin-converting enzyme 2 (ACE2, angiotensin-converting enzyme homolog, ACEH, ACE- related carboxypeptidase, metalloprotease MPROT15, EC: 3.4.17.23) soluble extracellular domain fragment (3-598, 1-596 in the current sequence), enzymatically inactive variant (H³⁵⁷>N³⁵⁵, H³⁶¹>N³⁵⁹), fused to human immunoglubulin G1 Fc fragment (h-CH2-CH3-CHS domains [Homo sapiens IGHG1*01 (hinge C⁶⁰¹>S (597-611), CH2 (612-721), CH3 P⁸²⁶>T (722-826), CHS (827-828))]), fused to human immunoglobulin M (IgM) C-terminal tail fragment (829-846), covalent pentamer of dimers, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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