Корамитуг

Rec. INN (наименование, зарегистрированное ВОЗ)

2626841-92-5

immunoglobulin G1-kappa, anti-[Homo sapiens TTR (transthyretin) misfolded], monoclonal antibody;
gamma1 heavy chain (1-454) [VH (Mus musculus IGHV5-12-2*01 (92.9%) -(IGHD) -IGHJ4*01 (84.6%) S123>L (119), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 CH1 R120, E12, M14 (CH1 R120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 E12 (363), M14 (365) (348-452), CHS (453-454)) (125-454)], (227-219')-disulfide with kappa light chain (1'-219') [V-KAPPA (Mus musculus IGKV2-137*01 (89.0%) -IGKJ2*03 (90.9%) S120>Q (105'), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (158'), V101 (196') (113'-219')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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