Крексавибарт
CrexavibartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2599039-61-7
Химическое название
immunoglobulin G1-lambda2, anti-[severe acute respiratory syndrome (human) coronavirus 2 (SARS- CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-460) [VH (Homo sapiens IGHV3-53*01 (97.9 %) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.25] (26-33.51-57.96-120)) (1-131) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v24 CH3 L107, S114 (CH1 R120 (228) (132-229), hinge 1-15 (230-244), CH2 (245-354), CH3 E12 (370), M14 (372), M107>L (442), N114>S (448) (355-459), CHS K2>del (460)) (132-460)], (234-215')-disulfide with lambda2 light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV2-14*03 (100%) - IGLJ1*01 (100%), CDR-IMGT [9.3.10] (26-34.52-54.91-100)) (1'-110') -Homo sapiens IGLC2*01 (100%) (111'-216')]; dimer (240-240'':243-243'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain Homo sapiens (1-460) [VH (Homo sapiens IGHV3-53*01 (97.9 %) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.25] (26-33.51-57.96-120)) (1-131) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v24 CH3 L107, S114 (CH1 R120 (228) (132-229), hinge 1-15 (230-244), CH2 (245-354), CH3 E12 (370), M14 (372), M107>L (442), N114>S (448) (355-459), CHS K2>del (460)) (132-460)], (234-215')-disulfide with lambda2 light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV2-14*03 (100%) - IGLJ1*01 (100%), CDR-IMGT [9.3.10] (26-34.52-54.91-100)) (1'-110') -Homo sapiens IGLC2*01 (100%) (111'-216')]; dimer (240-240'':243-243'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Crexavibartum (латинское)
- Crexavibart (английское)
- Crexavibart (немецкое)
- Crexavibart (французское)
- Crexavibart (испанское)
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