Далникастобарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2642171-59-1

immunoglobulin G1-kappa, anti-[Homo sapiens CD40 (tumor necrosis factor receptor superfamily member 5, TNFRSF5, p50)], Homo sapiens antibody;
gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV1-2*02 (98.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.19] (26-33.51-58.97-115)) (1-126) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1, G1v47 CH2 G1.1del (CH1 R120>K (223) (127-224), hinge 1-15 (225-239), CH2 G1.1>del (240-348), CH3 E12 (364), M14 (366) (349-453), CHS K2>del (454)) (127-454)], (229-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (94.7%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (153), V101 (191) (108'-214')]; dimer (235-235'':238-238'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from CHO-K1 cell line, lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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