Дазодалибеп

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

DB19025

2245953-10-8

engineered binding protein (1-85) anti-(human CD40 ligand) derived from the human tenascin third fibronectin type III domain (785-869), fused via the peptidyl linker ⁸⁶GGGGGGGGGGGGGGG¹⁰⁰ to engineered binding protein (101-190) anti-(human CD40 ligand) derived from the human tenascin third fibronectin type III domain (780-869), fused via the peptidyl linker ¹⁹1GGGGGGGGGG²⁰⁰ to human albumin (201-785), variant (C³⁴>S²³⁴), produced in Escherichia coli; [tenascin (785-869)-peptide (1-85) (containing a third fibronectin type III domain), engineered for binding to the CD40 ligand (CD40L)]-[G₁₅ linker (86-100)]-[tenascin (780-869)-peptide (101-190) (containing a third fibronectin type III domain), engineered for binding to the CD40 ligand (CD40L)]-[G₁₀ linker (91-100)]-[(C³⁴>S)-human serum albumin (HSA)] fusion protein, produced in Escherichia coli

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