Дазукибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

DB18429

2639474-65-8

immunoglobulin G1-kappa, anti-[Homo sapiens IFNB1 (Interferon beta)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-69*11 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v14-1 CH2 A1.3, A1.2, A1 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237) , G1>A (239) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS K2>del (448)) (120-448)], (222-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-16*01 (87.8%) -IGKJ4*01 (91.7%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%) Km3, A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

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