Делпацибарт
DelpacibartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2653183-66-3
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens TFRC (transferrin receptor, TfR1)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-2*06 (87.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v14 CH2 A1.3, A1.2, G1v48 CH2 R113 (CH1 R120 (213) (117-214), hinge 1-15 (215-229), CH2 L1.3>A (233), L1.2>A (234), L113>R (327) (230-339), CH3 E12 (355), M14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-214)-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-NL1*01 (84.2%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (225-225'': 228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-2*06 (87.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v14 CH2 A1.3, A1.2, G1v48 CH2 R113 (CH1 R120 (213) (117-214), hinge 1-15 (215-229), CH2 L1.3>A (233), L1.2>A (234), L113>R (327) (230-339), CH3 E12 (355), M14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-214)-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-NL1*01 (84.2%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (225-225'': 228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Delpacibartum (латинское)
- Delpacibart (английское)
- Delpacibart (немецкое)
- Delpacibart (французское)
- Delpacibart (испанское)
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