Деникитуг

Prop. INN (наименование, предложенное ВОЗ)

2865822-82-6

immunoglobulin G1-kappa, anti-[Homo sapiens CCR8 (C-C motif chemokine receptor 8, CKR-L1, CDw198)];
H-gamma1 heavy chain (1-451) [VH Musmus/Homsap (Mus musculus IGHV10-1*02 (90.9%) -(IGHD) -IGHJ1*01 (82.4%) A120>Q (113)/Homo sapiens IGHV3-73*01 (90.0%) -(IGHD) -IGHJ3*01 (92.9%) M123>T (116), CDR-IMGT [8.10.12] (26-33.51-60.99-110)) (1-121) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-219')-disulfide with L-kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV2-137*01 (91.3%) -IGKJ1*02 (90.0%) L124>V (109')/Homo sapiens IGKV2-28*01 (89.0%) -IGKJ4*01 (91.7%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158'), V101 (196') (113'-219')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO) cell line, derived from the cell line CHO-K1SV, co-expressing the enzyme glutamine synthetase (GS), and lacking the enzyme alpha-(1,6)-fucosyltransferase (FUT8), glycoform alfa

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