Денракибарт

Prop. INN (наименование, предложенное ВОЗ)

2922866-66-6

immunoglobulin G2-kappa, anti-[Homo sapiens CCL17 (C-C motif chemokine ligand 17, chemokine (C-C motif) ligand 17, small inducible cytokine subfamily A (Cys-Cys) member 17, SCYA17, thymus and activation-regulated chemokine, TARC)], Homo sapiens monoclonal antibody;
H-gamma2 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV5-51*01 (98.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG2*01 G2m.. CH2 V45.1, G2v3 CH2 A1.2, A1, S2, A30, L92, S115, S116 (CH1 P92>T (193) (122-219), hinge 1-12 (220-231), CH2 V1.2>A (235), G1>A (237), P2>S (238), H30>A (268), V45.1 (282), V92>L (309), A115>S (330), P116>S (331) (232-340), CH3 (341-445), CHS (446-447)) (341-447)], (135-220')-disulfide with L-kappa light chain Homo sapiens (1'-220') [V-KAPPA  (Homo sapiens IGKV4-1*01 (92.1%) -IGKJ1*01 (100%), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')]; dimer (223-223'':224-224'':227-227'':230-230'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa

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