Дивесиран

Divesiran

МНН

Rec. INN (наименование, зарегистрированное ВОЗ)

CAS

2646704-10-9

Химическое название

all-P-ambo-5'-O-{21-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-9,9-bis{12-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-7-hydroxy-7-sulfanylidene-2,6,8-trioxa-7λ5-phosphadodecan-1-yl}-1,16-dihydroxy-1,16-bis(sulfanylidene)-2,7,11,15,17-pentaoxa-1λ5,16λ5-diphosphahenicosan-1-yl}-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'- deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-deoxy-2'-fluoro-P-thioguanylyl-(3'→5')-2'-O-methyl-P-thiouridylyl- (3'→5')-2'-deoxy-2'-fluorouridine, duplex with all-P-ambo-2'-O-methyl-P-thioadenylyl-(3'→5')-2'- deoxy-2'-fluoro-P-thioadenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyladenylyl- (3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methylguanylyl- (3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methyladenylyl- (3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-deoxy-2'-fluoro-P-thioguanylyl-(3'→5')-2'-O-methyladenosine

Химическая формула

C434H570F19N145O270P40S10

Молярная масса

14058,53 г/моль

Структура

Структура Дивесиран

Иностранные названия

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