Донитабарт

Prop. INN (наименование, предложенное ВОЗ)

2888594-15-6

immunoglobulin G1-kappa, anti-[Homo sapiens GD2 (disialoganglioside GD2)];
H-gamma1 heavy chain (1-443) [VH (Homo sapiens IGHV1-2*06 (82.3%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.6] (26-33.51-58.97-102)) (1-113) -Homo sapiens IGHG1*01v, G1m17,1>G1m3,1 CH1 R120, CH3 D12, L14, G1v21 CH2 Y15.1, T16, E18, G1v20 A105 (CH1 R120 (210) (114-211), hinge 1-15 (212-226), CH2 M15.1>Y (248), S16>T (250), T18>E (252), K105>A (318) (227-336), CH3 D12 (352), L14 (354) (337-441), CHS (442-443)) (114-443)], (216-220')-disulfide with L-kappa light chain (1'-220') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-110*01 (87.0%) -IGKJ5*01 (91.7%) A120>Q (105')/Homo sapiens IGKV2D-29*02 (81.0%) -IGKJ2*01 (90.9%) I126>L (112'), CDR-IMGT [11.3.10] (27'-37'.55'-57'.94'-103')) (1'-113') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (159'), V101 (197') (114'-220')]; dimer (222-222'':225-225'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa

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