Доруксапапоген ралаплазмид

Rec. INN (наименование, зарегистрированное ВОЗ)

2416305-95-6

DNA plasmid encoding a fusion protein consisting of E6 and E7 proteins from human papilloma virus (HPV) types 11 and 6, with each protein coding sequence separated by a furin P2A cleavage site in the order HPV11 E6/furin peptide/HPV11 E7/furin peptide/HPV6 E6/furin peptide/HPV6 E7, having an N-terminal immunoglobulin E (IgE) leader sequence, driven by a human cytomegalovirus (CMV) immediate-early promoter and terminated by the bovine growth hormone polyadenylation signal (bGH polyA). The plasmid also contains a pUC origin of replication and a kanamycin resistance gene.

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