Дувакитуг

Rec. INN (наименование, зарегистрированное ВОЗ)

2750005-84-4

immunoglobulin G1-lambda, anti-[Homo sapiens TNFSF15 (tumor necrosis factor (TNF) superfamily member 15, vascular endothelial cell growth inhibitor, VEGI, TNF superfamily ligand TL1A)], Homo sapiens monoclonal antibody; gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-8*01 (92.9%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119)-Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 D12 (358), L14 (360) (343-447), CHS K2>del (448)) (120-448)], (222-215')-disulfide with lambda light chain Homo sapiens(1'-216') [V-LAMBDA (Homo sapiens IGLV1- 40*01 (85.7%) -IGLJ2*01 (90.9%), CDR-IMGT [9.3.10] (26-34.52-54.91-100)) (1'-110') -Homo sapiens IGLC2*01 (100%) (111'-216')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa

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