Эбдарокимаб
EbdarokimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens IL12B (interleukin 12B, CLMF, IL-12B, NKSF, CLMF2)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV5-51*01 (84.7%) -(IGHD) -IGHJ3*02 (92.9%)) CDR-IMGT [8.8.12] (26-33.51-58.97-108) (1-119) -Homo sapiens IGHG1*03v G1m3>G1m17, nG1m1 (CH1 R120>K (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449) (120-449)], (222-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3D-11*02 (86.7%) -IGKJ5*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV5-51*01 (84.7%) -(IGHD) -IGHJ3*02 (92.9%)) CDR-IMGT [8.8.12] (26-33.51-58.97-108) (1-119) -Homo sapiens IGHG1*03v G1m3>G1m17, nG1m1 (CH1 R120>K (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449) (120-449)], (222-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3D-11*02 (86.7%) -IGKJ5*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Ebdarokimabum (латинское)
- Ebdarokimab (английское)
- Ebdarokimab (немецкое)
- Ebdarokimab (французское)
- Ebdarokimab (испанское)
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