Эбласакимаб
EblasakimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2445460-16-0
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens IL13RA1 (interleukin 13 receptor subunit alpha 1, CD213a1)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV5-51*01 (98.0%) -(IGHD) -IGHJ1*01 (85.7%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, G4v5 h P10 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-211')-disulfide with kappa light chain Homo sapiens (1'-211') [V-KAPPA (Homo sapiens IGKV3-20*01 (97.9%) -IGKJ1*01 (100%), CDR-IMGT [7.3.5] (27-33.51-53.90-94)) (1'-104') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (150), V101 (188) (105'-211')];
dimer (224-224'':227-227'')-bisdisulfide, produced in a Chinese hamster ovary (CHO) cell line derived from CHO-K1, glycoform alfa
gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV5-51*01 (98.0%) -(IGHD) -IGHJ1*01 (85.7%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, G4v5 h P10 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-211')-disulfide with kappa light chain Homo sapiens (1'-211') [V-KAPPA (Homo sapiens IGKV3-20*01 (97.9%) -IGKJ1*01 (100%), CDR-IMGT [7.3.5] (27-33.51-53.90-94)) (1'-104') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (150), V101 (188) (105'-211')];
dimer (224-224'':227-227'')-bisdisulfide, produced in a Chinese hamster ovary (CHO) cell line derived from CHO-K1, glycoform alfa
Структура
Иностранные названия
- Eblasakimabum (латинское)
- Eblasakimab (английское)
- Eblasakimab (немецкое)
- Éblasakimab (французское)
- Eblasakimab (испанское)
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